Offices in Keller, Coppell, & Roanoke

Keller, TX: 817-431-6555
Coppell, TX: 469-312-7302
Roanoke, TX: 682-237-2271

Offices in Keller, Coppell, & Roanoke

Keller, TX: 817-431-6555
Coppell, TX: 469-312-7302
Roanoke, TX: 682-237-2271

Tirzepatide vs Semaglutide: Which One Is Better For Weight Loss

There are two medicines that have become more frequently used in the past few years: Tirzepatide and Semaglutide. These medicines are often used for weight loss.  Meanwhile, Tirzepatide has been considered more effective than Semaglutide or any other medication. 

However, there is still some research needed to prove that Tirzepatide is the best medication for weight loss. These drugs can make you feel like your stomach is full without eating anything. That’s why these medicines have become more and more popular nowadays. 

But of course, people who are aware of this medication mostly need clarification and have a question in their mind: if these two medicines are that effective for weight loss, then which is better for weight loss, Tirzepatide or Semaglutide?

We have answered all your questions and explained through research which medicine is better for weight loss. Keep reading to find out more about these two medicines.

What is Tirzepatide

TIrzapatide is used for the treatment of type 2 diabetes. It is a glucagon-like peptide-1 (GLP-1) receptor and glucose-dependent insulinotropic polypeptide (GIP) receptor. 

It is taken with a healthy diet and proper exercise to control blood sugar. It is used to lose weight and helps patients dealing with obesity.

  • How Does Tirzepatide Work?

Tirzepatide activates the GIP receptors. GIP is a hormone that is released from the gut after eating. GIP helps stimulate the release of insulin from the pancreas in a way that your blood sugar doesn’t get too low. This means that insulin is released when blood sugar levels are high, helping to regulate blood glucose levels after meals.

Moreover, Tirzepatide also activates the GLP-1 receptors. GLP-1 is another hormone that is released from the gut after eating. 

By activating both GIP and GLP-1 receptors, tirzepatide provides a dual mechanism to help regulate blood sugar levels and promote weight loss in people with type 2 diabetes.

What is Semaglutide

Semaglutide is a medication that is also prescribed by doctors to control your blood sugar level.  It is often prescribed for patients dealing with type 2 diabetes. It can reduce the risk of heart attack, stroke and death in type 2 diabetes patients.

It contains amino acids that lower your blood sugar level and insulin. This drug also produces GLP-1(which is naturally produced in our intestines). 

  • How Does Semaglutide Work?

It produces a hormone in our body called GLP-1.  The GLP-1 affects our blood sugar levels and calorie intake. It affects the part of your brain that controls your hunger or appetite. It dominates the hunger hormones that make you crave a meal. 

As a result, when this happens in your body, you don’t feel hungry and consume a low-calorie diet. This is how Semagltude helps you lose weight, reduces your hunger, and controls your blood sugar. It is very effective for obese patients.

Tirzepatide Vs. Semaglutide: Cost Overview

  • Tirzepatide Cost

Tirzepetide is usually sold under the brand name “Mounjaro” or “Zepbound.”

The Mounjaro would cost you around $1,069 per fill. A fill has four pens already in it, which is equal to your monthly dosage of Mounjaro. That means you have to pay around $12,800/ yearly. 

Meanwhile, the Zepbound would cost you around $1,060 for a month. But you don’t have to worry at all. If you have an insurance plan, your insurance would reduce the price of these drugs. If you have commercial insurance, you would only have to pay around $25 for a monthly dosage of Moujaro with a Mounjaro Saving card.

  • Semaglutide Cost

Semaglutide usually comes in two versions: “Branded” and “Generic.”  If you buy Semaglutide from a branded company, it would be expensive. The price range of Ozempic and Wegovy is between $1200 to $1300 a month—however, the generic form of Semaglutide starts from $100. 

Each 5 mg dose of ordinary Ozempic or Wegovy would cost you $249. A five-month dosage of Semaglutide would cost you around $930.

Tirzepatide & Semaglutide: Dosage Comparison 

  • Tirzepatide Dosage

The starting dose recommended for Mounjaro is 2.5 mg (it should be used one dose a week.) After a month, you can increase your dose to 5 mg weekly. The maximum dose allowed is 15 mg once a week.

  • Semaglutide Dosage

The Ozempic comes in an injection form. It is recommended to start with a 0.25 mg dose once a week, and after four weeks, you can increase it to 0.5 mg/ week. Your doctor can also recommend you increase 1 mg per week.

Pros and Cons of Tirzepatide


  • Your blood sugar might be managed
  • It will help you in weight management
  • You have to inject only once a week


  • You have to inject it by yourself
  • It might be required for use in the long term, but this can be more expensive for you.
  • There is a risk that if you stop the medication, you’ll regain weight.
  • It is not used specifically for weight loss.

Pros and Cons of Semaglutide 


  • It is proven to help you lose weight
  • It also manages blood sugar 
  • It is more effective than other weight loss medication


  • It is not certain that you will definitely lose weight from it.

How Long Does It Take For These Medications To Help In Weight Loss

Medicines like Semaglutide and Tirzepatide have shown incredible results. Just like using Semaglutide, it will show you its results within the first seven days of your course. In addition, you will see amazing results after 4 to 5 months of your course. 

Factors That Influence How Fast These Medications Help You In Weight Loss

If you want to achieve your desired results, then taking only these drugs isn’t enough. There are many other factors that affect how fast these medications help in your weight loss journey. Some of them are explained below:

  • Metabolic Process

The metabolic process is also another major factor in how these GLP-1 medications can affect your weight loss. That’s because people with high metabolic rates usually process medicines more quickly. 

Whereas patients with low metabolic rates need a longer period for these medications to work on them. That’s why, for people who have low metabolic rates, doctors prescribe them higher doses or more frequent doses to achieve the result in a short time. 

  • Healthy Lifestyle:

Eating fruits green vegetables, exercising daily and having an adequate sleep of atleast 7-8 hours will speed up your weight loss journey. As mentioned earlier, these medicines dominate our hunger hormones and reduce our appetite. As a result, your body can lack some nutrition.

So, it’s important to give your body the nutrients that are essential for your body. 

Possible Side Effects of These Medications

Some of the common side effects of using Tirzepatide/ Semaglutide  include 

  • Diarrhea 
  • fatigue
  • Dyspepsia
  • Diarrhea 
  • hair loss 
  • constipation
  • abdominal pain
  • Burping
  • Nausea 
  • Vomiting
  • Injection site reaction
  • Hypersensitivity reaction

In addition, if you face any of the following reactions, then immediately contact your doctor, if you have:

  • Thyroid tumour: you might face trouble in shallowing if you can’t breathe properly
  • Kidney problem: you will feel swelling in your ankles/ feet, have little or no urination, and feel tired.
  • Gallbladder problem: severe pain in the upper side of the stomach, nausea, bloating, heartburn, clay-coloured stool.
  • Side effect on eyesight: your vision will be blurred.
  • Low sugar symptoms: sweating, headache, hunger, fast heart rate, dizziness, confusion, weakness, hunger or irritability:

Is Tirzepatide Better than Semaglutide?

Semaglutide is an approved medicine used for the treatment of type 2 diabetes under the brand names Ozempic, Rybelsus, and Wegovy. When you eat, your digestive system releases the GLP-1 hormone, which signals the body to create more insulin. It can also send fullness signals to the brain.

Tirzepatide is sold under the brand name of Mounjaro. Tirzepatide mimics the GIP hormone and GLP-1 hormone in the body because this hormone makes you feel like your stomach is full and increases insulin production.

This means that tirzepatide might help you lose weight more than semaglutide. However, only type 2 diabetes patients can use it. In contrast, Semaglutide also has a big advantage in injection and tablet use. However, Tirzepatide only comes in the form of injection.

A test conducted by the National Center for Biotechnology Information reveals that tripeptide produces better results than semaglutide. Patients who took tirzepatide vs semaglutide had a different result. The results show that people who used tirzepatide had a significant loss in body weight compared to those who used Semaglutide.

Things To Consider While Buying Semaglutide and Tirzepatide Online

If you are looking to buy Semaglutide online, you have to consider a few important things before purchasing this medicine online. If you buy Semaglutide online without some precautions, you might risk your health and face the consequences.

  • Before buying this medicine online, you should verify the provider’s experience and ensure he has a license to sell these weight loss drugs.

These are some of the threats that you may face while purchasing these medicines:

  1. Beware of Fake Medicines

As people are heading towards buying from online platforms, some sellers might offer fake or counterfeit medications that look the same as the original ones. These counterfeit medicines contain some harmful ingredients that are harmful to your health.

  1. Avoid Fraud Websites 

When buying Semaglutide online, there are some websites where you can find Semaglutide at a cheaper price. They hook the customers with lower prices and sell them fake medicines, and they don’t even provide you with any kind of online assistance.

To avoid this threat, you must read their product reviews and check if they are FDA-approved.

Final TakeAway

To conclude, Tirzepatide and semaglutide are type 2 diabetes medicines that doctors often prescribe for obese patients looking for some kind of weight management medicine. 

Studies have shown that tirzepatide is more effective than Semaglutide. However, many studies are going on to see whether it is more effective for non-diabetic patients.

Ultimately, there are pros and cons attached to Tirzpatide and Semaglutide, but remember to consult with your doctor before using any of these medications because they can look for which option is best for your health.




12469 Timberland Blvd #501
Fort Worth, TX 76244

Fax: 817.431.7979



215 South Denton Tap Rd Suite 170 Coppell, TX 75019

Fax: 972.304.6050



206 Denton Dr
Roanoke, TX 76262

Fax: 682.237.2274



We accept several insurance providers. Check out the complete list to see if you are covered.