Semaglutide Before and After: Semaglutide Weight Loss Reviews

Ozempic is a groundbreaking medication that helps people lose weight and manage type 2 diabetes. The magic ingredient in Ozempic is semaglutide, a substance that acts like a natural hormone in our bodies that stops food cravings, regulates blood sugar, and reduces fat storage.

Some lucky people have been able to use this amazing drug, but many others are struggling with their health because of supply chain issues, insurance loopholes, and other problems. 

In this article, we share real-life stories of people who had incredible weight loss success with semaglutide, with their before and after pictures. We’ll also discuss some of the challenges people face with the drug and potential alternatives to help you lose weight.

Losing 40 lbs in 5 months on semaglutide (Ozempic)

Reddit user u/MamaVasy shared her fantastic weight loss results—a whopping 140 pounds lost in just five months. Their weight dropped from 95 lbs to 155 lbs with Ozempic, a calories-in-calories-out (CICO) diet, but no exercise. 

When other users asked if she worried about gaining the weight back if she stopped taking the meds, she agreed that this was one of her concerns. She said that her doctors told her that obesity and insulin resistance are chronic conditions that need lifelong treatment. 

She mentioned that Ozempic has been a blessing for her. Before, she tried to lose weight on her own for a long time without much success. Semaglutide changed the game for her because she didn’t need to depend solely on willpower. The medication transformed how her brain and body reacted to food, making it easier for her to resist cravings.

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Trouble getting a steady supply of semaglutide

Users like u/MamaVasy who got an Ozempic prescription from their healthcare provider are few. 

In many cases, people who want to get started on Ozempic are being turned away by their doctors for:

  • Not being in the “right” weight range
  • Not having the right insurance coverage, or 
  • A lack of supply.

Impact of Ozempic shortage on users

This lack of the drug has been extremely disturbing and can stop people from getting their health back. 

For example, Reddit user u/lifeuncommon asked how the original commenter got her Ozempic in the first place, as their doctor apparently wouldn’t even discuss Ozempic for weight loss with them. 

Another user shared that some women in their group therapy had tried Ozempic but got “cut off” when it was discovered that they were not insulin-resistant.

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Almost 90 lbs weight loss in a year on semaglutide

A Reddit user, u/pauwini1, lost nearly 90 lbs in about a year and a half. Being on Ozempic also helped her change her lifestyle and adopt healthier habits. Apart from eating an anti-inflammatory diet, she also exercised every day. 

As one user commented, she looked like she lost a whole person (in weight). 

Ozempic (semaglutide) made them lose 60 lbs in 10 months

Reddit user u/BananaMunchkinElf lost almost 60 pounds in about ten months. She started at 235 pounds and ended at 178 pounds. Her stunning pics show these incredible weight loss results.

Yet, many other people still encounter problems. Another participant in the Reddit discussion shared how happy they were with Ozempic. Unfortunately, they had to stop the meds for two months due to a shortage, which was highly frustrating. They shared that without Ozempic, they had to battle food noise and compulsive thoughts around food once again. 

User u/Worried-Fisherman-37 showed their before and after pics where they lost 50 lbs in 5 months but had to compound Ozempic on their own since their insurance would not cover the drug. Another user shared that because there isn’t enough Ozempic being produced, they had to seek alternate sources. 

While compounded Ozempic from pharmacies may work, it can get expensive. 

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Lost 60 lbs in just ten months 

u/jami_mccraney posted on Reddit that she went from 180 lbs to 120 lbs for a total of 60 lbs weight loss.

Semaglutide really changed the discussion around weight loss, obesity, and insulin resistance from that of ‘willpower’ to that of chemicals in the brain, hormonal balance, and metabolism.

For example, one Reddit user u/CZ-4life said that they were on Ozempic and had diabetes and finally felt “full” after they ate, and they wanted to know if that’s how naturally ‘skinny’ people felt all the time. The answer was yes! People who said they had been naturally skinny confirmed that they didn’t think about food all the time, felt hungry only rarely, and never knew what it felt like to want to keep eating until they felt sick. They shared that over time, this changed, and they ended up feeling hungry all day. After taking Ozempic, they felt like themselves again. 

One person, u/SkillfulFishy, said they had always wondered how some people could just walk away after eating just one cookie, but after going on Ozempic, they understood [that it was fixing the imbalance in their body].

So, if you struggle with your weight and have tried every diet, every weight loss hack, exercise, and more over the years, don’t lose hope. Generic Ozempic, semaglutide, may help. 

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64-pound weight loss with Ozempic; not pre-diabetic anymore

Reddit user u/K9MomofTwo shared her fabulous Ozempic weight loss pictures and explained that she lost 64 pounds on Ozempic. Before she started on the drug, she had been pre-diabetic, but after losing weight on Ozempic, her A1C dropped to 5. 

Another user shared on the same comment thread that they felt better overall, and even their knees were better, allowing them to become more active and mobile. 

u/mrogersjd shared that after being on Ozempic for about seven months, their A1C dropped to a normal range of 5 from the diabetic range of 7.5. Another fantastic result from this weight loss on Ozempic was that all other blood test results were also in the normal range!

How does semaglutide work for weight loss?

Ozempic, also known as semaglutide, can help you lose weight by: 

  • Craving control: By suppressing your appetite, semaglutide reduces constant thoughts about food, which prevents the urge to overeat.
  • Digestion regulation: Semaglutide mimics the hormone GLP-1. So, it slows down digestion, signaling fullness to your brain, and helps in appetite control.
  • Insulin boost: Semaglutide instructs your body to produce more insulin, a vital component for utilizing sugar as energy. This feature is particularly beneficial for individuals with insulin resistance (diabetes), supporting both weight loss and blood sugar level management.

Additionally, semaglutide (Ozempic and Wegovy) has been shown to improve heart health by reducing blood pressure and the risk of stroke.

How much weight can you lose on semaglutide?

Studies show that you can lose 15-20% of your body weight on GLP-1 agonist drugs like Semaglutide (Ozempic and Wegovy). As we’ve seen, users online have reported much greater weight loss numbers. 

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Is the Ozempic shortage over?

Unfortunately, the Ozempic shortage is real and far from over. Public health agencies around the world expect the shortage to worsen through 2024. Novo Nordisk, the Ozempic drug manufacturer, is expected to ration the starting doses of Ozempic. 

Even if there is some relief, the expectation is that there will be intermittent supply issues, at least through the first quarter of 2024. Users and people who want to start using Ozempic are left worrying about whether they will be able to get the doses they need, at an affordable cost, on a regular basis. 

How is the Ozempic shortage hurting people? 

A doctor on Reddit @DolmaSmuggler verified that there is a shortage of Ozempic and mentioned that the medication is likely on backorder in pharmacies well into 2024. The Ozempic shortage is directly from the manufacturer, so there is no way to get the drug, whether you pay out-of-pocket or are insured and qualify for the drug.

U/zfcjr67 commented that when they were on Ozempic, their A1C numbers were under control. However, with the Ozempic shortage, their doctor put them on another diabetes drug but that made their A1C shoot up and they felt terrible all the time.

Another user, u/Vegas_Steve, noted that he was enraged that his wife was approved to go on Ozempic over six months before but, due to the Ozempic shortage, couldn’t get started on her weight loss journey.

User  u/ThrowRASad_Movie135 said they had to stop their Ozempic medication because of the national shortage of the drug. They mentioned calling several pharmacies in and around their state and found that all of them did not have the drug. 

Another person stated that they felt the constant advertising for Ozempic and Wegovy was cruel because they fill you up with false hope and drive up demand for the drugs while there is no supply available.

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Final thoughts

Ozempic brought immense positive changes to many people across the country, many of whom generously share their remarkable weight loss journeys online. 

However, while some fortunate individuals secured insurance-approved prescriptions and a consistent supply of Ozempic, others faced substantial shortages for months. 

Buying the drug out-of-pocket is out of the question for millions because branded Ozempic and Wegovy are incredibly expensive. Adding to their worries, drug shortages from the manufacturers make it hard to get the medication consistently. 

People who want to start their weight loss journey for better health, blood glucose control, and lower their cardiovascular risk, need access to Ozempic and Wegovy now, not down the road. 

Because of these challenges, some people find relief in an Ozempic alternative—generic semaglutide, the active ingredient in the branded version. 

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